DOUXO S3 Calm Shampoo is a veterinary dermatology shampoo formulated specifically for pets with allergic, itchy, or inflamed skin. This shampoo contains an exclusive ingredient called Ophytrium, a purified natural extract that helps strengthen the skin barrier and soothe irritation. It’s clinically proven to reduce symptoms of allergic skin conditions (like itching and redness) in dogs us.douxo.com. DOUXO Calm is soap-free and very gentle, designed to restore skin balance by supporting the skin’s microbial flora and maintaining hydrationdouxo.com. Pet owners often use this on dogs with moderate to severe skin allergies, hot spots, or atopic dermatitis, often with guidance from a vet. The shampoo needs to sit on the skin for about 5-10 minutes before rinsing to allow the ingredients to work. While it’s a bit more expensive than over-the-counter shampoos, many reviews mention it’s worth it for dogs that constantly itch or get rashes, as it provides noticeable relief and reduces the need for other medications.

• Key Benefits: Medicated formula for allergy relief; contains Ophytrium to soothe itchy, irritated skin and support skin barrier douxo.com; paraben-free and fragrance-free.
• Ideal For: Dogs with serious allergies or chronic sensitive skin issues; those who need a veterinarian-recommended solution for itching, inflammation, or dermatitis.